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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XRCC1 All Species: 15.15
Human Site: S226 Identified Species: 33.33
UniProt: P18887 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P18887 NP_006288 633 69526 S226 S S A A S S A S P V S R A I G
Chimpanzee Pan troglodytes XP_512717 596 65689 L211 S P K G K R K L D L N Q E E K
Rhesus Macaque Macaca mulatta XP_001100256 645 69984 P258 D K D E A E A P S Q K V T V T
Dog Lupus familis XP_533653 654 71801 S249 S S A T S S P S A A S R A V G
Cat Felis silvestris
Mouse Mus musculus Q60596 631 68952 S228 S S A A S S A S P V P K V V G
Rat Rattus norvegicus Q9ESZ0 631 68817 S228 S S A A S S A S P V P K V G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516926 549 59237 S188 A G G Q P G P S Y A A A T L Q
Chicken Gallus gallus
Frog Xenopus laevis NP_001080711 651 73244 E225 A E S S S S T E K Q T V K T P
Zebra Danio Brachydanio rerio NP_001003988 615 68071 S225 A L K T E G S S T H T P A S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572217 614 68751 S224 S T A L R R L S A G K V S S L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001180271 512 56847 A150 S I P P S Q Q A S S S S S T S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.8 82.3 86 N.A. 86 86.5 N.A. 47.7 N.A. 53.9 51.1 N.A. 20.7 N.A. N.A. 38.8
Protein Similarity: 100 94.1 83 88.3 N.A. 91.1 91 N.A. 56.5 N.A. 67.7 68.8 N.A. 36.9 N.A. N.A. 55.1
P-Site Identity: 100 6.6 6.6 66.6 N.A. 73.3 73.3 N.A. 6.6 N.A. 13.3 13.3 N.A. 20 N.A. N.A. 20
P-Site Similarity: 100 26.6 20 73.3 N.A. 86.6 80 N.A. 26.6 N.A. 40 33.3 N.A. 33.3 N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 28 0 46 28 10 0 37 10 19 19 10 10 28 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 10 0 0 0 0 0 10 0 0 0 0 0 10 % D
% Glu: 0 10 0 10 10 10 0 10 0 0 0 0 10 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 10 10 0 19 0 0 0 10 0 0 0 10 37 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 0 10 19 0 10 0 10 0 10 0 19 19 10 0 10 % K
% Leu: 0 10 0 10 0 0 10 10 0 10 0 0 0 10 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % N
% Pro: 0 10 10 10 10 0 19 10 28 0 19 10 0 0 10 % P
% Gln: 0 0 0 10 0 10 10 0 0 19 0 10 0 0 10 % Q
% Arg: 0 0 0 0 10 19 0 0 0 0 0 19 0 0 0 % R
% Ser: 64 37 10 10 55 46 10 64 19 10 28 10 19 19 10 % S
% Thr: 0 10 0 19 0 0 10 0 10 0 19 0 19 19 10 % T
% Val: 0 0 0 0 0 0 0 0 0 28 0 28 19 28 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _